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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T74849 | EBL-3183 | ||
EBL-3183为一种吲哚-2-羧酸盐,作为有效的金属-β-内酰胺酶(MBL)抑制剂。它通过可逆结合、非共价及竞争性作用抑制NDM-1,其pIC50值为7.7。 | |||
T60239 | Metallo-β-lactamase-IN-6 | ||
Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lactamase-IN-6 exhibits potent synergistic antibacterial properties when combined with Meropenem, particularly against engineered Escherichia coli strains and clinically isolated Pseudomonas aeruginosa carrying the VIM-2 MBL gene [1]. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03565 |
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant
MBPD,MBP-C,mannose-binding lectin (protein C) 2, so... |
Human | CHO Cells |
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 24 kDa and the accession number is P11226. | |||
TMPJ-00133 |
MBL2 Protein, Mouse, Recombinant
Mannose binding lectin (C),MBL-2,Mannose-b... |
Mouse | HEK293 Cells |
Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phas... | |||
TMPY-00429 |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc)
MBL-C,mannose-binding lectin (protein C) 2... |
Mouse | HEK293 Cells |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 50.6 kDa and the accession number is P41317. | |||
TMPY-04322 |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His)
MBL-C,MBL,mannose-binding lectin (protein ... |
Mouse | HEK293 Cells |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P41317. | |||
TMPJ-00136 |
MBL2 Protein, Human, Recombinant (His)
Collectin-1,Mannose-Binding Lectin,COLEC1,Mannan-Binding Pro... |
Human | HEK293 Cells |
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These h... | |||
TMPH-03327 |
MBL2 Protein, Rat, Recombinant (His)
|
Rat | E. coli |
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession num... | |||
TMPK-00705 |
MASP2 Protein, Human, Recombinant (His)
MAP19,sMap,MASP-2,MASP1P1 |
Human | E. coli |
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population. | |||
TMPY-02596 |
GLT25D2 Protein, Human, Recombinant (His)
GLT25D2,RP11-498P10.2,collagen β(... |
Human | Baculovirus Insect Cells |
Glycosyl transferase 25 domain 2 (GLT25D2) is a glucosyltransferase enzyme expressed only at low levels in the nervous system. Glycosyltransferases are enzymes that act as a catalyst for the transfer of a monosaccharide unit from an activated nucleotide sugar (also known as the "glycosyl donor") to a glycosyl acceptor molecule, usually an alcohol. Glycosyl transferases transfer glycosyl groups onto their substrate. Localization partially defines their function. Glt25D2 enzyme showed a strong gal... | |||
TMPJ-00850 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Protein T1,suppression of tumorigenicity 2,Ly84,DER... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPY-00891 |
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4 |
Human | HEK293 Cells |
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2. | |||
TMPY-04113 |
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI... |
Human | E. coli |
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2. | |||
TMPY-01717 |
VEGF164 Protein, Mouse, Recombinant
vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子 |
Mouse | Baculovirus Insect Cells |
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2. | |||
TMPY-00341 |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2. | |||
TMPY-02096 |
TACI Protein, Human, Recombinant (His)
RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor... |
Human | HEK293 Cells |
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2. | |||
TMPY-02011 |
CD96 Protein, Human, Recombinant (His)
CD96 molecule,TACTILE |
Human | HEK293 Cells |
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2. | |||
TMPY-01442 |
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin |
Human | HEK293 Cells |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... | |||
TMPY-01613 |
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
A630052E07Rik,OSF-2,Osf2,PLF,AI74... |
Mouse | HEK293 Cells |
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2. | |||
TMPY-06056 |
KRAS Protein, Human, Recombinant (G12D, His)
KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL... |
Human | E. coli |
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2. | |||
TMPY-00751 |
TrkB Protein, Human, Recombinant (His)
trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec... |
Human | HEK293 Cells |
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2. | |||
TMPY-04844 |
BTN3A1 Protein, Human, Recombinant (His)
BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2... |
Human | HEK293 Cells |
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2. | |||
TMPY-05288 |
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
PLGF,PGFL,placental growth factor,D12S1900,SHGC-107... |
Human | E. coli |
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2. | |||
TMPY-02820 |
SDF-1 Protein, Human, Recombinant (isoform a)
SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1 |
Human | E. coli |
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2. | |||
TMPY-01691 |
Clusterin Protein, Human, Recombinant (CLU34, His)
SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP... |
Human | HEK293 Cells |
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2. | |||
TMPY-01985 |
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
FCGR2,FCGR21,CD32A,FCG2,... |
Human | HEK293 Cells |
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2. | |||
TMPY-04644 |
PDGFB Protein, Human, Recombinant (His)
platelet-derived growth factor beta polypeptide,SSV,c-sis,SI... |
Human | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted... | |||
TMPY-05414 |
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
D6H12S2489E,NKG2-D,killer cell le... |
Mouse | Baculovirus Insect Cells |
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2. | |||
TMPY-04396 |
C-ABL/ABL1 Protein, Human, Recombinant (GST)
v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k... |
Human | Baculovirus Insect Cells |
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an... | |||
TMPY-02500 |
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
Gp39,AW208766,Brp39,chitinase 3 like 1 |
Mouse | HEK293 Cells |
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2. | |||
TMPY-01935 |
c-Kit Protein, Human, Recombinant (His)
PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog... |
Human | HEK293 Cells |
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2. | |||
TMPY-04356 |
GSK3B Protein, Human, Recombinant (His)
glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β |
Human | Baculovirus Insect Cells |
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2. | |||
TMPY-01888 |
KRAS Protein,Human, Recombinant (Q61H, His)
KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho... |
Human | E. coli |
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2. | |||
TMPY-00747 |
Nectin-2 Protein, Human, Recombinant (His)
PVRR2,Nectin-2,poliovirus receptor-related... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2. | |||
TMPY-05427 |
CD19 Protein, Human, Recombinant (hFc)
CVID3,B4,CD19 molecule |
Human | HEK293 Cells |
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2. | |||
TMPJ-00335 |
TGFBR2 Protein, Mouse, Recombinant (His)
TGFR-2,TGF-beta type II receptor,Transforming growt... |
Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2. | |||
TMPY-04051 |
c-Kit Protein, Human, Recombinant (hFc)
SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h... |
Human | HEK293 Cells |
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2. | |||
TMPY-02792 |
GDNF Protein, Human, Recombinant (HEK293)
HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot... |
Human | HEK293 Cells |
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2. | |||
TMPY-01871 |
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
interleukin 5 receptor, alpha,IL5R,CD125,CDw12<... |
Human | HEK293 Cells |
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2. | |||
TMPY-01359 |
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2. | |||
TMPY-00127 |
M-CSF/CSF1 Protein, Human, Recombinant
集落刺激因子,CSF-1,MCSF,M-CSF,colony stimulating factor 1 (macroph... |
Human | HEK293 Cells |
M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2. | |||
TMPY-00005 |
FGF-8a Protein, Human, Recombinant
fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW... |
Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... | |||
TMPY-03425 |
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as... |
Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... | |||
TMPY-05586 |
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMIGD2,IGPR-1,transmembrane and immunoglobulin doma... |
Human | HEK293 Cells |
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu... | |||
TMPY-02432 |
VEGF164 Protein, Rat, Recombinant
血管内皮生长因子,vascular endothelial growth factor A |
Rat | Baculovirus Insect Cells |
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2. | |||
TMPY-00748 |
Nectin-2 Protein, Human, Recombinant
PRR2,Nectin-2,PVRR2,poliovirus re... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2. | |||
TMPY-00850 |
ST2/IL-1 RL1 Protein, Human, Recombinant
ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2. | |||
TMPY-00871 |
LAYN Protein, Human, Recombinant (hFc)
layilin |
Human | HEK293 Cells |
LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2. | |||
TMPY-00392 |
PAM Protein, Human, Recombinant (His)
PAL,peptidylglycine alpha-amidating monooxygenase,peptidylgl... |
Human | HEK293 Cells |
PAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 94.4 kDa and the accession number is P19021-2. | |||
TMPY-04116 |
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2 |
Human | E. coli |
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2. | |||
TMPY-04829 |
G-CSF Protein, Human, Recombinant
G-CSF,colony stimulating factor 3 (granulocyte),集落刺激因子,CSF3O... |
Human | HEK293 Cells |
G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2. | |||
TMPY-02231 |
TrkB Protein, Mouse, Recombinant (His)
trk-B,neurotrophic tyrosine kinase, receptor, type 2 |
Mouse | HEK293 Cells |
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2. | |||
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